A-BAND SHORTENING IN SINGLE FIBERS OF FROG SKELETAL-MUSCLE

被引：15

作者：

PERIASAMY, A ^{[1
]}

BURNS, DH ^{[1
]}

HOLDREN, DN ^{[1
]}

POLLACK, GH ^{[1
]}

TROMBITAS, K ^{[1
]}

机构：

[1] UNIV WASHINGTON,CTR BIOENGN WD-12,SEATTLE,WA 98195

来源：

BIOPHYSICAL JOURNAL | 1990年 / 57卷 / 04期

关键词：

D O I：

10.1016/S0006-3495(90)82601-1

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The question of whether A-bands shorten during contraction was investigated using two methods: high-resolution polarization microscopy and electron microscopy. During shortening from extended sarcomere lengths in the passive state, sarcomere-length changes were essentially accounted for by I-band shortening. During active shortening under otherwise identical conditions, the sarcomere length change was taken up approximately equally by A- and I-bands. Several potential artifacts that could give rise to apparent A-band shortening were considered and judged unlikely. Results obtained with polarization microscopy were similar to those obtained with electron microscopy. Thus, modest but significant thick filament shortening appears to occur during active sarcomere shortening under physiological conditions. © 1990, The Biophysical Society. All rights reserved.

引用

页码：815 / 828

页数：14

共 18 条

[1] MERCURIC-CHLORIDE IN ALCOHOL AND CHLOROFORM USED AS A RAPIDLY ACTING FIXATIVE FOR CONTRACTING MUSCLE-FIBERS [J].