AN INTRAMOLECULAR BAYLIS-HILLMAN REACTION

被引：103

作者：

ROTH, F ^{[1
]}

GYGAX, P ^{[1
]}

FRATER, G ^{[1
]}

机构：

[1] GIVAUDAN ROURE,DUBENDORF,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 08期

关键词：

BAYLIS-HILLMAN REACTION; INTRAMOLECULAR; ALPHA-HYDROXYALKYLATION OF ACRYLATES;

D O I：

10.1016/S0040-4039(00)91855-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By means of an intramolecular Baylis-Hillman reaction the cyclopentene derivative 1 has been formed from 2. Asymmetric induction is low (entry 12, table 1). In the sixmembered ring example 9 --> 10 the yield is only 17% - 23% (entries 1 and 2, table 2).

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页码：1045 / 1048

页数：4

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