PULMONARY-HYPERTENSION IN PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA

被引：45

作者：

HELLER, PG ^{[1
]}

GRINBERG, AR ^{[1
]}

LENCIONI, M ^{[1
]}

MOLINA, MM ^{[1
]}

RONCORONI, AJ ^{[1
]}

机构：

[1] UNIV BUENOS AIRES,INST INVEST MED ALFREDO LANARI,BUENOS AIRES,ARGENTINA

来源：

CHEST | 1992年 / 102卷 / 02期

关键词：

D O I：

10.1378/chest.102.2.642

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Pulmonary arterial hypertension (PAH) and cor pulmonale were found in a patient with paroxysmal nocturnal hemoglobinuria (PNH). Autopsy revealed widespread thromboses in pulmonary microvasculature. Vascular thromboses attributed to hypercoagulability have been found in PNH in many organs, including the lungs. PAH has not been reported, however. This disease should then be considered a rare cause of PAH.

引用

页码：642 / 643

页数：2

共 6 条

[1]

BEUTLER E, 1991, HEMATOLOGY, P188

[2] PAROXYSMAL NOCTURNAL HEMOGLOBINURIA - RELATION OF THE CLINICAL MANIFESTATIONS TO UNDERLYING PATHOGENIC MECHANISMS [J].

CROSBY, WH .

BLOOD, 1953, 8 (09) :769-812

[3] INTERACTIONS OF THE PLATELETS IN PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA WITH COMPLEMENT - RELATIONSHIP TO DEFECTS IN THE REGULATION OF COMPLEMENT AND TO PLATELET SURVIVAL INVIVO [J].

DEVINE, DV ;

SIEGEL, RS ;

ROSSE, WF .

JOURNAL OF CLINICAL INVESTIGATION, 1987, 79 (01) :131-137

[4]

FRASER RG, 1990, DIAGNOSIS DISEASES C, P1701

[5] PULMONARY-HYPERTENSION FROM CHRONIC PULMONARY THROMBOEMBOLISM [J].

RICH, S ;

LEVITSKY, S ;

BRUNDAGE, BH .

ANNALS OF INTERNAL MEDICINE, 1988, 108 (03) :425-434

[6]

ROSSE WF, 1990, BLOOD, V75, P1595

← 1 →