EXPRESSION AND LOCALIZATION OF GAMMA-AMINOBUTYRIC-ACID-A (GABA(A)) RECEPTOR ALPHA-1 SUBUNIT AND L-GLUTAMATE DECARBOXYLASE (GAD) MESSENGER-RNAS IN RAT RETINA - AN ANALYSIS BY IN-SITU HYBRIDIZATION

被引：11

作者：

KOSAKA, J ^{[1
]}

MORII, E ^{[1
]}

TANIGUCHI, M ^{[1
]}

KITAMURA, Y ^{[1
]}

NOMURA, S ^{[1
]}

FUKUDA, Y ^{[1
]}

机构：

[1] OSAKA UNIV, SCH MED, DEPT PATHOL, SUITA, OSAKA 565, JAPAN

来源：

MOLECULAR BRAIN RESEARCH | 1994年 / 25卷 / 1-2期

关键词：

RAT; RETINA; IN SITU HYBRIDIZATION; GABA(A) RECEPTOR ALPHA-1 SUBUNIT; L-GLUTAMATE DECARBOXYLASE; RETINAL GANGLION CELL; DIGOXIGENIN-LABELED CRNA;

D O I：

10.1016/0169-328X(94)90294-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The localization of the mRNAs encoding gamma-aminobutyric acid(A) receptor alpha 1 subunit (GABA(A) alpha 1) and L-glutamate decarboxylase (GAD) was elucidated in the rat retina by in situ hybridization. Soma diameter analysis of signal positive cells in the ganglion cell layer demonstrated that a subpopulation including alpha-cells of retinal ganglion cells expressed GABA(A) alpha 1 mRNA and a subpopulation of ganglion cells smaller than alpha-cells expressed GAD mRNA.

引用

页码：163 / 167

页数：5

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