CARBOLINES .7. ANISIDINES, CONVENIENT TOOLS TO SYNTHESIZE HYDROXY-BETA-CARBOLINES

被引：11

作者：

ROCCA, P ^{[1
]}

MARSAIS, F ^{[1
]}

GODARD, A ^{[1
]}

QUEGUINER, G ^{[1
]}

ADAMS, L ^{[1
]}

ALO, B ^{[1
]}

机构：

[1] UNIV LAGOS,DEPT CHEM,LAGOS,NIGERIA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1995年 / 32卷 / 04期

关键词：

D O I：

10.1002/jhet.5570320412

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The paper describes a convenient synthesis of hydroxy-beta-carbolines from commercial anisidines based on key steps such as metalation, cross-coupling and cyclization. The first total synthesis of a major cytotoxic constituent of a marine bryozoan is also reported, the 8-hydroxy-1-vinyl-beta-carboline.

引用

页码：1171 / 1175

页数：5

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