INSULIN-LIKE GROWTH-FACTORS AND CANCER

被引：273

作者：

LEROITH, D

BASERGA, R

HELMAN, L

ROBERTS, CT

机构：

[1] THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, JEFFERSON CANC CTR, PHILADELPHIA, PA 19107 USA

[2] NCI, PEDIAT BRANCH, MOLEC ONCOL SECT, BETHESDA, MD 20892 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1995年 / 122卷 / 01期

关键词：

D O I：

10.7326/0003-4819-122-1-199501010-00009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The insulin-like growth factor (IGF) family of peptides, binding proteins, and receptors are important for normal human growth and development and are involved in the specialized functions of most physiologic systems. Most members of the IGF system are expressed by different cancer cells and may play an important role in the propagation of these malignancies. New therapies aimed at modulating various components of the IGF system could affect the progression and metastasis of cancer.

引用

收藏

页码：54 / 59

页数：6

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