BRAIN-TUMORS AND THE OCCURRENCE OF SEVERE INVASIVE BASAL-CELL CARCINOMA IN 1ST DEGREE RELATIVES WITH GORLIN SYNDROME

被引：38

作者：

EVANS, DGR

BIRCH, JM

ORTON, CI

机构：

[1] UNIV MANCHESTER,PATERSON INST CANC RES,CRC,DEPT CANC GENET,MANCHESTER M13 9PL,LANCS,ENGLAND

[2] UNIV MANCHESTER,CRC,PAEDIAT & FAMILIAL CANC RES GRP,MANCHESTER M13 9PL,LANCS,ENGLAND

[3] CHRISTIE HOSP & HOLT RADIUM INST,DEPT PLAST SURG,MANCHESTER M20 9BX,LANCS,ENGLAND

来源：

BRITISH JOURNAL OF NEUROSURGERY | 1991年 / 5卷 / 06期

关键词：

BASAL CELL CARCINOMA; GORLIN SYNDROME; MEDULLOBLASTOMA; RADIOTHERAPY;

D O I：

10.3109/02688699109002890

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe the occurrence of a medulloblastoma and an astrocytoma in successive generations of a family with the Gorlin syndrome. The appearance of thousands of invasive basal cell carcinomata after craniospinal irradiation led to the death of one patient from intracranial involvement.

引用

页码：643 / 646

页数：4

共 11 条

[1]

BRIDGES BA, 1982, ATAXIA TELANGIECTASI

[2]

FEATHERSTONE T, 1982, AM J HUM GENET, V35, P58

[3] MULTIPLE NEVOID BASAL-CELL EPITHELIOMA, JAW CYSTS AND BIFID RIB - A SYNDROME [J].