1ST PREPARATION OF MITOMYCINS SPECIFICALLY LABELED WITH DEUTERIUM AT THE C6-METHYL POSITION

被引：16

作者：

KANDA, Y ^{[1
]}

KASAI, M ^{[1
]}

机构：

[1] KYOWA HAKKO KOGYO CO LTD,TOKYO RES LABS,MACHIDA,TOKYO 194,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 08期

关键词：

D O I：

10.1021/jo00295a051

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C6-methyl group of mitomycins was specifically labeled with deuterium. 7,7-(Ethylenedioxy)mitomycin (8), a masked quinonoid compound derived from mitomycin A (2), played an important role in this methodology. © 1990, American Chemical Society. All rights reserved.

引用

页码：2515 / 2518

页数：4

共 9 条

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