EFFECT OF LEISHMANIA-MAJOR ON HUMAN POLYMORPHONUCLEAR LEUKOCYTE FUNCTION-INVITRO

被引：21

作者：

ALTUWAIJRI, AS

ALMOFLEH, IA

MAHMOUD, AA

机构：

[1] KING SAUD UNIV, COLL MED, DEPT MED, RIYADH 11461, SAUDI ARABIA

[2] KING SAUD UNIV, COLL MED, DEPT PARASITOL, RIYADH 11461, SAUDI ARABIA

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 1990年 / 32卷 / 03期

基金：

日本学术振兴会;

关键词：

D O I：

10.1099/00222615-32-3-189

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

The effect of various antigens of Leishmania major promastigotes on the function of human polymorphonuclear leucocytes (PMNLs) was examined. Different concentrations of L. major antigens were incubated with isolated PMNLs for various periods and the respiratory burst was assessed by Luminol-dependent chemiluminescence. All the Leishmania antigens employed inhibited the PMNL respiratory burst by 35-64%. PMNL viability was not affected either by the concentrations or type of the parasite antigen. Oxygen free radical scavengers enhanced the action of the antigens on the PMNL respiratory burst.

引用

页码：189 / 193

页数：5

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[2]

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[4]

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