COMPUTED TOMOGRAPHIC DEMONSTRATION OF BRAIN CHANGES IN INCONTINENTIA PIGMENTI

Incontinentia pigmenti is a rare condition, which may involve the CNS. Computed tomographic (CT) examination can supply important information about the dynamics and pathologic nature of this poorly understood syndrome. Two patients suffering from incontinentia pigmenti were examined by CT because of CNS symptoms. Large low-density areas in the brain were demonstrated in the CT examination of the first patient a few days after birth, suggesting a local edema. Diffuse brain atrophy was found 2 yr later. Brain atrophy was also found in the 2nd patient in a CT examination done at the age of 11 yr.