GLUTATHIONE CONJUGATION AND DNA-BINDING OF (+/-)-TRANS-7,8-DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE AND (+/-)-7-BETA,8-ALPHA-DIHYDROXY-9-ALPHA,10-ALPHA-EPOXY-7,8,9,10-TETRAHYDROBENZO[A]PYRENE IN ISOLATED RAT HEPATOCYTES

被引：82

作者：

JERNSTROM, B

BABSON, JR

MOLDEUS, P

HOLMGREN, A

REED, DJ

机构：

[1] MIT, DEPT NUTR & FOOD SCI, CAMBRIDGE, MA 02139 USA

[2] KAROLINSKA INST, DEPT CHEM, S-10401 STOCKHOLM 60, SWEDEN

[3] OREGON STATE UNIV, CORVALLIS, OR 97331 USA

来源：

CARCINOGENESIS | 1982年 / 3卷 / 08期

关键词：

D O I：

10.1093/carcin/3.8.861

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：861 / 866

页数：6

共 39 条

[1] PROTECTIVE ROLE OF THE GLUTATHIONE REDOX CYCLE AGAINST ADRIAMYCIN-MEDIATED TOXICITY IN ISOLATED HEPATOCYTES [J].

BABSON, JR ;

ABELL, NS ;

REED, DJ .

BIOCHEMICAL PHARMACOLOGY, 1981, 30 (16) :2299-2304

[2]

BAIRD WM, 1975, CANCER RES, V35, P54

[3]

BOROUJERDI M, 1981, CANCER RES, V41, P951

[4] TUMORIGENICITY OF OPTICAL ENANTIOMERS OF DIASTEREOMERIC BENZO[A]PYRENE 7,8-DIOL-9,10-EPOXIDES IN NEWBORN MICE - EXCEPTIONAL ACTIVITY OF(+)-7-BETA, 8-ALPHA-DIHYDROXY-9-ALPHA, 10-ALPHA-EPOXY-7,8.9.10-TETRAHYDROBENZOL[A]PYRENE [J].

BUENING, MK ;

WISLOCKI, PG ;

LEVIN, W ;

YAGI, H ;

THAKKER, DR ;

AKAGI, H ;

KOREEDA, M ;

JERINA, DM ;

CONNEY, AH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (11) :5358-5361

[5]

BURKE MD, 1977, J BIOL CHEM, V252, P6424

[6] CYTOCHROME P-450-LINKED ACTIVATION OF 3-HYDROXYBENZO(ALPHA)PYRENE [J].

CAPDEVILA, J ;

JERNSTROM, B ;

VADI, H ;

ORRENIUS, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 65 (03) :894-900

[7]

Chasseaud L F, 1979, Adv Cancer Res, V29, P175, DOI 10.1016/S0065-230X(08)60848-9

[8] THE ENZYME-CATALYZED CONVERSION OF ANTI-BENZO[A]PYRENE-7,8-DIOL 9,10-OXIDE INTO A GLUTATHIONE CONJUGATE [J].

COOPER, CS ;

HEWER, A ;

RIBEIRO, O ;

GROVER, PL ;

SIMS, P .

CARCINOGENESIS, 1980, 1 (12) :1075-1080

[9]

FELSENFELD GARY, 1965, J MOL BIOL, V13, P407

[10]

FRIEDBERG T, 1979, J BIOL CHEM, V254, P2028

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