ASYMMETRIC BIOCHEMICAL REDUCTION, ACYLATION AND HYDROLYSIS IN THE (DIENE)FE(CO)3 SERIES - EXPERIMENTAL RESULTS AND MOLECULAR MODELING STUDIES

被引：27

作者：

HOWELL, JAS ^{[1
]}

PALIN, MG ^{[1
]}

JAOUEN, G ^{[1
]}

TOP, S ^{[1
]}

ELHAFA, H ^{[1
]}

CENSE, JM ^{[1
]}

机构：

[1] ECOLE NATL SUPER CHIM,F-75231 PARIS 05,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 06期

关键词：

D O I：

10.1016/S0957-4166(00)80235-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric reduction using bakers yeast and asymmetric acyl transfer using porcine pancreatic lipase may be used in the kinetic resolution and desymmetrization of acyclic (diene)Fe(CO)3 complexes bearing CHO and CH2OH substituents respectively. The results may be interpreted in terms of current active site models for these biotranformations.

引用

页码：1241 / 1252

页数：12

共 39 条

[1] ENZYMATIC RESOLUTION OF A CHIRAL ORGANOMETALLIC ESTER - ENANTIOSELECTIVE HYDROLYSIS OF 2-ETHOXYCARBONYLBUTA-1,3-DIENETRICARBONYLIRON BY PIG-LIVER ESTERASE [J].