REDUCTION OF DIGOXIN EFFECT DURING THE DIGOXIN-QUINIDINE INTERACTION

被引：9

作者：

DAS, G

BARR, CE

CARLSON, J

机构：

[1] VET ADM MED CTR, FARGO, ND 58102 USA

[2] N DAKOTA STATE UNIV, COLL PHARM, FARGO, ND 58105 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 1984年 / 35卷 / 03期

关键词：

D O I：

10.1038/clpt.1984.36

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effects of the digoxin-quinidine interaction on cardiac function was examined in healthy subjects. While serum digoxin levels were elevated, the improved cardiac function due to digoxin evidently declined during combined therapy. An alternate explanation for the changes previously interpreted as enhanced digitalis effects during the interaction is provided.

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页码：317 / 321

页数：5

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