ISOLATION AND CHARACTERIZATION OF SEROLOGICALLY REACTIVE LIPOOLIGOSACCHARIDES FROM MYCOBACTERIUM-TUBERCULOSIS

被引：13

作者：

PAPA, F

CRUAUD, P

LUQUIN, M

THOREL, MF

GOH, KS

DAVID, HL

机构：

[1] UNIV AUTONOMA BARCELONA,HOSP SANTA CRUZ & SAN PABLO,DEPT MICROBIOL,E-0825 BARCELONA,SPAIN

[2] CNEVA,LCRV,F-94703 MAISONS ALFORT,FRANCE

来源：

RESEARCH IN MICROBIOLOGY | 1993年 / 144卷 / 02期

关键词：

GLYCOLIPID; MYCOBACTERIUM-TUBERCULOSIS; LOS; TUBERCULOSIS; CHARACTERIZATION; ANTIGENICITY; DIAGNOSIS;

D O I：

10.1016/0923-2508(93)90021-S

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Two major highly polar antigenic glycolipids were isolated from recent isolates of Mycobacterium tuberculosis from a wide range of geographical origins. The occurrence of these polar glycolipids was demonstrated by isolation, purification and chromatographic characterization and/or serological procedures in 12 strains. Based on their chromatographic properties, these polar glycolipids belong to the lipooligosaccharide family. Preliminary data on the use of these newly described antigens in the serodiagnosis of tuberculosis is presented.

引用

页码：91 / 99

页数：9

共 26 条

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BAER HH, 1992, IN PRESS CARBOHYD RE

[2] ISOLATION AND EXPRESSION OF A GENE-CLUSTER RESPONSIBLE FOR BIOSYNTHESIS OF THE GLYCOPEPTIDOLIPID ANTIGENS OF MYCOBACTERIUM-AVIUM [J].