INHIBITION OF NUCLEIC-ACID SYNTHESIS BY DI-N-BUTYL ESTER OF METHOTREXATE

被引：19

作者：

CURT, GA ^{[1
]}

TOBIAS, JS ^{[1
]}

KRAMER, RA ^{[1
]}

ROSOWSKY, A ^{[1
]}

PARKER, LM ^{[1
]}

TATTERSALL, MHN ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,SIDNEY FARBER CANC CTR,DIV MED CHEM & PHARMACOL,BOSTON,MA 02215

来源：

BIOCHEMICAL PHARMACOLOGY | 1976年 / 25卷 / 17期

关键词：

D O I：

10.1016/0006-2952(76)90047-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1943 / 1946

页数：4

共 12 条

[1]

EISENFELD A. J., 1962, PROC AMER ASSOC CANCER RES, V3, P316

[2]

FISCHER GA, 1961, BIOCHEM PHARMACOL, V7, P75

[3]

FOLEY GE, 1965, CANCER, V18, P522, DOI 10.1002/1097-0142(196504)18:4<522::AID-CNCR2820180418>3.0.CO

[4]

2-J

[5]

JOHNS DG, 1973, DRUG METAB DISPOS, V1, P580

[6] ANTINEOPLASTIC ACTIVITY OF LIPID-SOLUBLE DIALKYL ESTERS OF METHOTREXATE [J].

JOHNS, DG ;

FARQUHAR, D ;

CHABNER, BA ;

WOLPERT, MK ;

ADAMSON, RH .

EXPERIENTIA, 1973, 29 (09) :1104-1105

[7] INCREASED DIHYDROFOLATE REDUCTASE ACTIVITY AS A POSSIBLE BASIS OF DRUG RESISTANCE IN LEUKAEMIA [J].

MISRA, DK ;

GOLDIN, A ;

HUMPHREYS, SR ;

FRIEDKIN, M ;

CRAWFORD, EJ .

NATURE, 1961, 189 (475) :39-+

[8] BIOCHEMICAL AND PHARMACOLOGIC STUDIES WITH 1-BETA-D-ARABINOFURANOSYLCYTOSINE 5'-ADAMANTOATE (NSC-117614), A DEPOT FORM OF CYTARABINE [J].

NEIL, GL ;

BUSKIRK, HH ;

MOXLEY, TE ;

MANAK, RC ;

KUENTZEL, SL ;

BHUYAN, BK .

BIOCHEMICAL PHARMACOLOGY, 1971, 20 (12) :3295-&

[9] METHODICHLOROPHEN AS ANTITUMOR DRUG [J].

PRICE, LA ;

GOLDIE, JH ;

HILL, BT .

BRITISH MEDICAL JOURNAL, 1975, 2 (5961) :20-21

[10] METHOTREXATE ANALOGS .2. FACILE METHOD OF PREPARATION OF LIPOPHILIC DERIVATIVES OF METHOTREXATE AND 3',5'-DICHLOROMETHOTREXATE BY DIRECT ESTERIFICATION [J].

ROSOWSKY, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (10) :1190-1193

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