THE RB GENE LOCATES ON CHROMOSOME-15 AT BAND-15Q13 IN THE SYRIAN-HAMSTER

被引：5

作者：

SATOH, H

EBERT, R

WISEMAN, RW

BARRETT, JC

机构：

[1] NIEHS,MOLEC CARCINOGENESIS LAB,RES TRIANGLE PK,NC 27709

[2] UNIV WURZBURG,INST PHARMACOL & TOXICOL,W-8700 WURZBURG,GERMANY

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 65卷 / 1-2期

关键词：

D O I：

10.1159/000133617

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The retinoblastoma susceptibility gene, which encodes a nuclear phosphoprotein (Rb), plays an important role in cell-cycle progression in both normal development and tumorigenesis. Using a Syrian hamster cDNA probe homologous to the human retinoblastoma gene (RB), we have localized the gene to chromosome band 15q13 by conventional in situ hybridization.

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页码：127 / 129

页数：3

相关论文

共 24 条

[1]

BARRETT JC, 1984, PHARMACOL REV, V36, P535

[2] REPORT OF THE COMPARATIVE COMMITTEE FOR HUMAN, MOUSE AND OTHER RODENTS [J].

DAVISSON, MT ;

LALLEY, PA ;

PETERS, J ;

DOOLITTLE, DP ;

HILLYARD, AL ;

SEARLE, AG .

CYTOGENETICS AND CELL GENETICS, 1991, 58 (3-4) :1152-1189

[3] TRANSFER OF CHINESE-HAMSTER CHROMOSOME-1 TO MOUSE CELLS AND REGIONAL ASSIGNMENT OF 7 GENES - A COMBINATION OF GENE-TRANSFER AND MICROCELL FUSION [J].

DHAR, V ;

SEARLE, BM ;

ATHWAL, RS .

SOMATIC CELL AND MOLECULAR GENETICS, 1984, 10 (06) :547-559

[4]

DiPaolo J A, 1979, Prog Exp Tumor Res, V24, P2

[5]

Harnden DG, 1985, INT SYSTEM HUMAN CYT

[6] LOCALIZATION OF SINGLE COPY DNA-SEQUENCES ON G-BANDED HUMAN-CHROMOSOMES BY INSITU HYBRIDIZATION [J].

HARPER, ME ;

SAUNDERS, GF .

CHROMOSOMA, 1981, 83 (03) :431-439

[7] ASSIGNMENT OF THE NRAS PROTOONCOGENE TO CHROMOSOME-12 OF SYRIAN-HAMSTER BY INSITU HYBRIDIZATION [J].

ISSA, T ;

PORTER, R ;

PARRY, EM ;

PARRY, JM .

CYTOGENETICS AND CELL GENETICS, 1992, 60 (3-4) :241-244

[8] LOSS OF TUMOR-SUPPRESSIVE FUNCTION DURING CHEMICALLY-INDUCED NEOPLASTIC PROGRESSION OF SYRIAN-HAMSTER EMBRYO CELLS [J].

KOI, M ;

BARRETT, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (16) :5992-5996

[9]

LALLEY PA, 1978, P NATL ACAD SCI USA, V75, P2383

[10] MOUSE CHROMOSOME-14 [J].

NADEAU, JH ;

COX, R .

MAMMALIAN GENOME, 1992, 3 :S206-S219