A METHOD FOR TESTING THE NONRANDOMNESS OF CHROMOSOMAL BREAKPOINTS

被引：17

作者：

TAI, JJ

HOU, CD

WANGWUU, S

WANG, CH

LEU, SY

WUU, KD

机构：

[1] NATL YANG MING MED COLL,INST GENET,TAIPEI,TAIWAN

[2] VET GEN HOSP,DIV COLORECTAL SURG,TAIPEI,TAIWAN

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 63卷 / 03期

关键词：

D O I：

10.1159/000133523

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Testing the nonrandomness of breakage at a chromosome band is an essential step for identifying a fragile site. In this paper, we propose a method derived by using the relationship between the binomial and F distributions for testing nonrandomness. The method is simple in calculation. It was applied to the detection of fragile sites for Chinese patients with colorectal carcinoma.

引用

页码：147 / 150

页数：4

共 23 条

[1] 2 METHODS FOR MEASURING THE NON-RANDOMNESS OF CHROMOSOME-ABNORMALITIES [J].