ASSESSMENT OF MAJOR CARCINOGENS AND ALKALOIDS IN THE TOBACCO AND MAINSTREAM SMOKE OF USSR CIGARETTES

被引:28
作者
DJORDJEVIC, MV
SIGOUNTOS, CW
HOFFMANN, D
BRUNNEMANN, KD
KAGAN, MR
BUSH, LP
SAFAEV, RD
BELITSKY, GA
ZARIDZE, D
机构
[1] UNIV KENTUCKY,DEPT AGRON,LEXINGTON,KY 40546
[2] ACAD MED SCI USSR,CANC RES CTR,MOSCOW 115478,USSR
关键词
D O I
10.1002/ijc.2910470306
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Tobacco and mainstream smoke of USSR cigarettes were analyzed for carcinogens. The pH values of suspensions of the tobacco (5.4-5.6) and the nitrate content of the tobaccos (0.4-1.7%) were as expected for flue-cured and sun-cured tobaccos and mixtures thereof. The nicotine levels of the cigarette tobaccos (0.76-0.94%) and total alkaloid content (0.85-1.08%) were relatively low compared with tobaccos used in Western European and US cigarettes. The concentrations of tobacco-specific N-nitrosamines in the cigarette tobaccos were also low (N'-nitrosonornicotine 0.36-0.85-mu-g/g) compared with those in bright, oriental and blended cigarette tobaccos in Western countries (0.3-19-mu-g/g). The 2 non-filter and 4 filter cigarettes from the USSR had slow burning rates and yielded 14.0-16.7 puffs/cigarette, while puff yields for commercial cigarettes in Western countries average less-than-or-equal-to 11 puffs/cigarette. Consequently, tar and benzo(a)pyrene yields in the smoke of all cigarettes as well as nitrosamine yields were high, especially in the smoke of the filter cigarettes. It appears that an increase in the burning rates of these cigarettes should lead to lower smoke yields.
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页码:348 / 351
页数:4
相关论文
共 31 条
[1]  
BOKELMAN GH, 1985, BEITR TABAKFORSCH, V13, P29
[2]   ROLE OF TOBACCO STEMS IN THE FORMATION OF N-NITROSAMINES IN TOBACCO AND CIGARETTE MAINSTREAM AND SIDESTREAM SMOKE [J].
BRUNNEMANN, KD ;
MASARYK, J ;
HOFFMANN, D .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1983, 31 (06) :1221-1224
[3]   ASSESSMENT OF THE CARCINOGENIC N-NITROSODIETHANOLAMINE IN TOBACCO PRODUCTS AND TOBACCO-SMOKE [J].
BRUNNEMANN, KD ;
HOFFMANN, D .
CARCINOGENESIS, 1981, 2 (11) :1123-1127
[4]   INFLUENCE OF TEMPERATURE AND HUMIDITY ON THE ACCUMULATION OF TOBACCO-SPECIFIC NITROSAMINES IN STORED BURLEY TOBACCO [J].
BURTON, HR ;
BUSH, LP ;
DJORDJEVIC, MV .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1989, 37 (05) :1372-1377
[5]  
CASTONGUAY A, 1990, Journal of Cancer Research and Clinical Oncology, V116, P92
[6]   IMPROVED METHOD FOR THE QUANTIFICATION OF NITRITE IN PLANT MATERIALS [J].
CRUTCHFIELD, J ;
BURTON, HR .
ANALYTICAL LETTERS, 1989, 22 (03) :555-571
[7]  
DIKUN P P, 1959, Vopr Onkol, V5(7), P34
[8]   IDENTIFICATION AND ANALYSIS OF A NICOTINE-DERIVED N-NITROSAMINO ACID AND OTHER NITROSAMINO ACIDS IN TOBACCO [J].
DJORDJEVIC, MV ;
BRUNNEMANN, KD ;
HOFFMANN, D .
CARCINOGENESIS, 1989, 10 (09) :1725-1731
[9]   TOBACCO-SPECIFIC NITROSAMINE ACCUMULATION AND DISTRIBUTION IN FLUE-CURED TOBACCO ALKALOID ISOLINES [J].
DJORDJEVIC, MV ;
GAY, SL ;
BUSH, LP ;
CHAPLIN, JF .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1989, 37 (03) :752-756
[10]  
DJORDJEVIC MV, 1990, IN PRESS CORESTA S P