BIOCONVERSION OF DRIMENOL INTO 3-BETA-HYDROXYDRIMANES BY ASPERGILLUS-NIGER - EFFECT OF CULTURE ADDITIVES

被引：14

作者：

RAMIREZ, HE ^{[1
]}

CORTES, M ^{[1
]}

AGOSIN, E ^{[1
]}

机构：

[1] CATHOLIC UNIV CHILE,FAC INGN,DEPT INGN QUIM,SANTIAGO,CHILE

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 05期

关键词：

D O I：

10.1021/np50095a014

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The bioconversion of (-)-drimenol [1) and drimenyl acetate [2] into the corresponding 3beta-hydroxydrimanes by Aspergillus niger in agitated liquid cultures was investigated. Initial hydroxylation yields of 2% and 10%, respectively, were obtained. However, drimenyl acetate hydroxylation increased to 18% when Carbopol-934 was added. The highest transformation yield (33%) was reached when an inclusion complex of drimenyl acetate to beta-cyclodextrin (1:1 w/w) was added to the cultures, after 48 h of cultivation. The effect on growth and transformation yields of both additivies is discussed.

引用

页码：762 / 764

页数：3