THERAPEUTIC EFFICACY, SECONDARY EFFECTS, AND PATIENT ACCEPTABILITY OF 10-PERCENT SULFUR IN EITHER PORK FAT OR COLD CREAM FOR THE TREATMENT OF SCABIES

被引:16
作者
AVILAROMAY, A [1 ]
ALVAREZFRANCO, M [1 ]
RUIZMALDONADO, R [1 ]
机构
[1] NATL AUTONOMOUS UNIV MEXICO, NATL INST PEDIAT, DEPT DERMATOL, MEXICO CITY 04510, DF, MEXICO
关键词
D O I
10.1111/j.1525-1470.1991.tb00844.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Twenty-six children with scabies and 32 contacts were treated with 10% sulfur in cold cream. A 100% clinical cure rate was observed, although 56.8% of patients experienced some kind of mild, transient cutaneous reaction. An additional 25 children with scabies and 28 contacts were treated with 10% sulfur and 1% salicylic acid in pork fat. Of these, 88% were clinically cured and 73.5% had some cutaneous adverse effects. In both groups, most adverse effects were related to skin dryness or postscabetic reaction. The cold cream base was more acceptable to patients than the pork fat base. However, the pork fat base was significantly cheaper and easier to obtain than the cold cream base, and 238 times less expensive than the cheapest commercial scabicidal medication available in the United States.
引用
收藏
页码:64 / 66
页数:3
相关论文
共 13 条
[1]  
Ruiz-Maldonado R, Violante MN., La sarna nueva epidemia, Rev Salud Publica Mex, 12, pp. 801-809, (1970)
[2]  
Orkin M., Resurgence of scabies, JAMA, 217, pp. 593-595, (1971)
[3]  
Garza TM., Sarna, estudio general, reporte de 1000 casos, Rev Med UNAM, 1182, pp. 265-272, (1974)
[4]  
Saul A., Escabiasis, Temas de dermatología pediátrica, pp. 57-64, (1980)
[5]  
Rasmussen JE., Lindane, Arch Dermatol, 123, pp. 1008-1010, (1987)
[6]  
Aquiles C., Tratamiento de la sarna con crema de crotamiton, Invest Med Int, 3, pp. 241-244, (1976)
[7]  
Mellanby K., The development of symptoms, parasitic infection and immunity in human scabies, Parasitology, 35, pp. 197-206, (1944)
[8]  
Mellanby K., Scabies, (1972)
[9]  
Basch F., Uber schwefelwasser stoffvergiftung bei ausserlicher applikation von elementaren schwefel in salbenform, Arch Experiment Path Pharm, 111, pp. 126-132, (1926)
[10]  
Schultz MW, Gomez M, Hansen RC, Et al., Comparative study of 5% permethrin cream and 1% lindane lotion for the treatment of scabies, Arch Dermatol, 126, pp. 167-170, (1990)