RECOVERY OF CLINICALLY IMPORTANT MICROORGANISMS FROM THE BACT/ALERT BLOOD CULTURE SYSTEM DOES NOT REQUIRE TESTING FOR 7 DAYS

被引:66
作者
WILSON, ML
MIRRETT, S
RELLER, LB
WEINSTEIN, MP
REIMER, LG
机构
[1] ROBERT WOOD JOHNSON UNIV HOSP, MICROBIOL LAB, NEW BRUNSWICK, NJ USA
[2] UNIV MED & DENT NEW JERSEY, ROBERT WOOD JOHNSON MED SCH, DEPT MED, NEW BRUNSWICK, NJ 08903 USA
[3] UNIV MED & DENT NEW JERSEY, ROBERT WOOD JOHNSON MED SCH, DEPT PATHOL, NEW BRUNSWICK, NJ 08903 USA
[4] DEPT VET AFFAIRS MED CTR, MICROBIOL LAB, SALT LAKE CITY, UT USA
[5] UNIV UTAH, SCH MED, DEPT MED, SALT LAKE CITY, UT 84112 USA
[6] UNIV UTAH, SCH MED, DEPT PATHOL, SALT LAKE CITY, UT 84112 USA
[7] DUKE UNIV, MED CTR, CLIN MICROBIOL LAB, DURHAM, NC 27710 USA
[8] DUKE UNIV, MED CTR, DEPT PATHOL, DURHAM, NC 27710 USA
[9] DUKE UNIV, MED CTR, DEPT MED, DURHAM, NC 27710 USA
关键词
D O I
10.1016/0732-8893(93)90127-S
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Recently, we published a comparison of the BacT/Alert blood culture system with the BACTEC 6601730 nonradiometric blood culture system using blood inocula of 5 ml per bottle. By reanalyzing data collected during that study, we found that, for true-positive isolates causing bacteremia or fungemia, 363 (97.6%) of 376 and 341 (97.7%) of 349 isolates were recovered by the end of day 5 of testing, and 364 (97.9%) of 376 and 343 (98.3%) of 349 isolates were recovered by the end of day 6 of testing for aerobic and anaerobic bottles, respectively. Most isolates recovered on days 6 (24 of 27) and 7 (20 of 25) of testing were either contaminants or indeterminate as a cause of sepsis. When used as recommended by the manufacturer, only six (1 .3%) of 464 clinically important isolates recovered on test days 6-7 would have gone undetected had testing been limited to 5 days and four (0.9%) of 464 had testing been limited to 6 days. We conclude that BacT/Alert bottles can be tested for as few as 5 days and then discarded with minimal loss of true-positive isolates and maximal reduction of contaminants.
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收藏
页码:31 / 34
页数:4
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