LARYNGEAL MANIFESTATIONS OF GOUT

被引:23
作者
GUTTENPLAN, MD
TOWNSEND, MJ
HENDRIX, RA
BALSARA, G
机构
[1] HOSP UNIV PENN,DEPT OTORHINOLARYNGOL & HUMAN COMMUN,PHILADELPHIA,PA 19104
[2] MED COLL PENN,DEPT PATHOL,PHILADELPHIA,PA 19129
关键词
GOUT; LARYNX;
D O I
10.1177/000348949110001108
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Gout is a disorder of purine metabolism characterized by hyperuricemia with rare involvement of the head and neck. We present a 72-year-old woman with a known history of gout who presented with hoarseness and a lesion suspicious for carcinoma of the larynx. Endoscopic biopsy revealed a tophus of the true vocal cord with characteristic birefringent crystalline deposits and giant cell granuloma. There have been limited reports of gouty involvement of the larynx, more commonly involving cricoarytenoid arthritis. Tophi of the laryngeal soft tissues are exceedingly rare. In this paper we will discuss the pathophysiology and management of this interesting clinical entity.
引用
收藏
页码:899 / 902
页数:4
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