WHY DOES THE GASTRIC BYPASS CONTROL TYPE-2 DIABETES-MELLITUS

被引:61
作者
PORIES, WJ
机构
[1] Department of Surgery, East Carolina University, Greenville, North Carolina
关键词
DIABETES; GASTRIC BYPASS; GLUCOSE METABOLISM; GUT HORMONES; INSULIN; SEVERE OBESITY;
D O I
10.1381/096089292765559891
中图分类号
R61 [外科手术学];
学科分类号
摘要
The remarkable control of diabetes by the gastric bypass remains to be explained. Although it may be totally due to the weight loss induced by the operation, it is likely that the detour of the hormonally active foregut plays a role as well. This keynote address explores the pathophysiology of non-insulin-dependent diabetes mellitus and reviews the data which support the thesis that the gastric antrum, duodenum, and proximal jejunum modulate glucose metabolism and insulin action.
引用
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页码:303 / 313
页数:11
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