METALATION OF PYRIDINE N-OXIDES AND APPLICATION TO SYNTHESIS

被引：22

作者：

MONGIN, O ^{[1
]}

ROCCA, P ^{[1
]}

THOMASDITDUMONT, L ^{[1
]}

TRECOURT, F ^{[1
]}

MARSAIS, F ^{[1
]}

GODARD, A ^{[1
]}

QUEGUINER, G ^{[1
]}

机构：

[1] INST NATL SCI APPL ROUEN, IRCOF,CHIM ORGAN FINE & HETEROCYCL LAB,CNRS, URA 1429, F-76131 MONT ST AIGNAN, FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 19期

关键词：

D O I：

10.1039/p19950002503

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regio- and chemi-selective, directed ortho-lithiation of 2-, 2,5- or 3,4-substituted pyridine N-oxides has been achieved with diisopropylamide and butyllithium. Polysubstituted pyridine N-oxides, azaxanthone, and an isomer of orelline have been synthesized by such methods.

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页码：2503 / 2508

页数：6

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