LOOKING INTO THE GROOVES OF DNA

被引：39

作者：

BOUTONNET, N

HUI, XW

ZAKRZEWSKA, K

机构：

[1] Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique, Paris, 75005, rue Pierre et Marie Curie

来源：

BIOPOLYMERS | 1993年 / 33卷 / 03期

关键词：

D O I：

10.1002/bip.360330314

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present study is aimed at understanding the effects of DNA sequence, local conformation, and curvature on groove geometry. Energy-optimized structures are obtained by Jumna methodology; groove geometry is analyzed by a recently developed technique that allows an accurate and continuous measurement of width and depth. The mechanics of groove deformations is also studied and analyzed in terms of helicoidal parameters.

引用

页码：479 / 490

页数：12

共 24 条

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