HEMODYNAMICS OF SEASONAL ADAPTATION

被引：69

作者：

IZZO, JL

LARRABEE, PS

SANDER, E

LILLIS, LM

机构：

[1] The Departments of Medicine, University of Rochester School of Medicine and Dentistry New York, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, New York

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1990年 / 3卷 / 05期

关键词：

Blood pressure; Cardiac output; Seasonal hemodynamics;

D O I：

10.1093/ajh/3.5.405

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

To investigate the possibility that seasonal adaptation requires significant hemodynamic changes, 5 normotensive and 21 mildly hypertensive subjects were followed through 4 seasons for changes in systemic hemodynamics and sympathetic nervous activity. In the upright position wintertime blood pressures increased by 3% (P = NS) over summer values whereas cardiac output and stroke volume decreased by 18% and 21%, respectively (P <. 0017 for each). Similarly, wintertime upright heart rate increased by 7% (P <. 017) with larger parallel increases in systemic vascular resistance (+24%, P <. 0017) and plasma norepinephrine (+26%, P <. 017). The supine values followed similar trends but the magnitude of changes was about 50% less than the corresponding upright values. Thus, in the northern US, wintertime vasoconstriction is related to increased sympathetic nervous activity and decreased cardiac output. When these reciprocal changes are proportional, blood pressure remains constant. © 1990 by the American Journal of Hypertension, Ltd.

引用

页码：405 / 407

页数：3

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