LIMB SALVAGE FOR MALIGNANT BONE-TUMORS IN YOUNG-CHILDREN

被引：31

作者：

CARA, JA

CANADELL, J

机构：

[1] Departments of Orthopaedics and Traumatology, Clínica Universitária de Navarra, Universidad de Navarra, Pamplona

[2] Orthopaedic Surgery, Clínica Universitária de Navarra, Universidad de Navarra, Pamplona

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS | 1994年 / 14卷 / 01期

关键词：

ALLOGRAFT; BONE GRAFT; EWINGS SARCOMA; OSTEOSARCOMA;

D O I：

10.1097/01241398-199401000-00022

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

From March 1984 to April 1991, the Orthopaedics Department of the Clinica Universitaria de Navarra treated 47 cases of malignant bone tumors in young children by limb-salvage surgery. Mean follow-up time was 4.4 years. The histologic diagnoses were osteosarcoma (33 cases) and Ewing's sarcoma (14 cases). All patients were treated following the Cancer Protocol of the Clinica Universitaria de Navarra. We used allograft reconstruction in 26 patients, autograft reconstruction in seven; and nonbiologic material in seven other patients. Thirty-six of these patients are alive currently; 11 have died. The overall survival rate was 76.6%. Three patients suffered local recurrences, and seven developed metastatic disease. The most significant complications were infection in four cases, and osteosynthesis anchorage detachment in eight cases. We believe that with recent medical, surgical, and rehabilitative advances, limb-salvage surgery has surpassed amputation as the primary treatment for malignant bone tumors in young children.

引用

页码：112 / 118

页数：7

共 56 条

[1]

Alho A., Karaharju E.O., Korkala O., Lassonen E.M., Holm-Strom T., Muller C., Allogeneic grafts for bone tumor, Acta Orthop Scand, 60, pp. 143-153, (1989)

[2]

Bacci G., Picci P., Gitelis S., Borghi A., Campanacci M., The treatment of localized Ewing’s sarcoma. The experience at the Istituto Ortopédico Rizzoli in 163 cases treated with and without adjuvant chemotherapy, Cancer, 49, pp. 1561-1570, (1982)

[3]

Bacci G., Toni A., Avella M., Long-term results in 144 localized Ewing’s sarcoma patients treated with combined therapy, Cancer, 63, pp. 1477-1486, (1989)

[4]

Brown K., Limb reconstruction with vascularized fibular grafts after bone tumor resection, Clin Orthop, 262, pp. 64-73, (1991)

[5]

Cammisa F.P., Glasser D.B., Otis J.C., Kroll M.A., Lane J.M., Healey J.H., The Van Ness tibial rotationplasty: A functionally viable reconstructive procedure in children who have a tumor of the distal end of the femur, J Bone Joint Surg [Am], 72, pp. 1541-1547, (1990)

[6]

Campanacci M., Bacci G., Bertoni F., Picci P., Minutillo A., Franceschi C., The treatment of osteosarcoma of the extremities: Twenty year’s experience at the Istituto Ortopédico Rizzoli, Cancer, 48, pp. 1569-1586, (1981)

[7]

Canadell J., Protocolos terapêuticos Del Cancer De La Clínica Universitária De Navarra, pp. 313-325, (1984)

[8]

Canadell J., Forriol F., Cara J.A., New technique in oncologic surgery: Physeal distraction, J Bone Joint Surg [Br]

[9]

Cara J.A., Amillo S., Prótesis de resección de rodilla en la cirugía reconstructiva tumoral, Rev Ortop Traum, 36, pp. 39-42, (1992)

[10]

Cara J.A., Amillo S., Canadell J., La prótesis de resección de rodilla en la cirugía reconstructiva tumoral: Estúdio comparativo entre el uso del aloinjerto y espaciador plástico, Rev Med Univ Navarra, 36, pp. 69-75, (1991)

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