NEW BROAD-SPECTRUM AMINOGLYCOSIDE ANTIBIOTIC, G-52, PRODUCED BY MICROMONOSPORA-ZIONENSIS

被引：20

作者：

MARQUEZ, JA ^{[1
]}

WAGMAN, GH ^{[1
]}

TESTA, RT ^{[1
]}

WAITZ, JA ^{[1
]}

WEINSTEIN, MJ ^{[1
]}

机构：

[1] SCHERING CORP, BLOOMFIELD, NJ 07003 USA

来源：

JOURNAL OF ANTIBIOTICS | 1976年 / 29卷 / 05期

关键词：

D O I：

10.7164/antibiotics.29.483

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

G-52 is a new broad spectrum aminoglycoside produced by a species of the genus Micromonospora, M. zionensis. It was differentiated from other known related antibiotics by a variety of chemical and biological methods. Its in vitro and in vivo spectrum of activity appears to be quite similar to that of verdamicin and gentamicin but is differentiated from them by its increased activity against 6''-N-acetylating strains.

引用

页码：483 / 487

页数：5

共 7 条

[1] STRUCTURE OF ANTIBIOTIC G-52, A NEW AMINOCYCLITOL-AMINOGLYCOSIDE ANTIBIOTIC PRODUCED BY MICROMONOSPORA-ZIONENSIS [J].