STRUCTURAL STUDIES ON BIOACTIVE COMPOUNDS .8. SYNTHESIS, CRYSTAL-STRUCTURE, AND BIOLOGICAL PROPERTIES OF A NEW SERIES OF 2,4-DIAMINO-5-ARYL-6-ETHYLPYRIMIDINE DIHYDROFOLATE-REDUCTASE INHIBITORS WITH INVIVO ACTIVITY AGAINST A METHOTREXATE-RESISTANT TUMOR-CELL LINE

被引：24

作者：

GRIFFIN, RJ

MEEK, MA

SCHWALBE, CH

STEVENS, MFG

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 11期

关键词：

D O I：

10.1021/jm00131a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2468 / 2474

页数：7

共 26 条

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