ERROR-PRONE SOS REPAIR CAN BE ERROR-FREE

被引：15

作者：

LIU, SK

TESSMAN, I

机构：

[1] Department of Biological Sciences, Purdue University West Lafayette

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1990年 / 216卷 / 04期

关键词：

D O I：

10.1016/S0022-2836(99)80001-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Most of the mutagenesis that accompanies the SOS repair of ultraviolet light-induced lesions in the single-stranded DNA of phage S13 is eliminated when the groES or the groEL gene of Escherichia coli is defective. Therefore, this SOS mutagenesis is not a necessary consequence of what is commonly called error-prone repair, but is additionally imposed on the repair system by the GroE heat shock proteins, which are responsible for the assembly of polypeptides into multimeric structures. © 1990 Academic Press Limited.

引用

收藏

页码：803 / 807

页数：5

相关论文

共 27 条

[1] INDUCIBILITY OF A GENE-PRODUCT REQUIRED FOR UV AND CHEMICAL MUTAGENESIS IN ESCHERICHIA-COLI [J].

BAGG, A ;

KENYON, CJ ;

WALKER, GC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (09) :5749-5753

[2] SYNTHESIS OF RECA PROTEIN AND INDUCTION OF BACTERIOPHAGE-LAMBDA IN SINGLE-STRAND DEOXYRIBONUCLEIC ACID-BINDING PROTEIN MUTANTS OF ESCHERICHIA-COLI [J].

BALUCH, J ;

CHASE, JW ;

SUSSMAN, R .

JOURNAL OF BACTERIOLOGY, 1980, 144 (02) :489-498

[3]

BONNER CA, 1988, J BIOL CHEM, V263, P18946

[4] UMUD MUTAGENESIS PROTEIN OF ESCHERICHIA-COLI - OVERPRODUCTION, PURIFICATION, AND CLEAVAGE BY RECA [J].

BURCKHARDT, SE ;

WOODGATE, R ;

SCHEUERMANN, RH ;

ECHOLS, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (06) :1811-1815

[5] GROE MUTANTS OF ESCHERICHIA-COLI ARE DEFECTIVE IN UMUDC-DEPENDENT UV MUTAGENESIS [J].

DONNELLY, CE ;

WALKER, GC .

JOURNAL OF BACTERIOLOGY, 1989, 171 (11) :6117-6125

[6] NEW RECA MUTATIONS THAT DISSOCIATE THE VARIOUS RECA PROTEIN ACTIVITIES IN ESCHERICHIA-COLI PROVIDE EVIDENCE FOR AN ADDITIONAL ROLE FOR RECA PROTEIN IN UV MUTAGENESIS [J].

DUTREIX, M ;

MOREAU, PL ;

BAILONE, A ;

GALIBERT, F ;

BATTISTA, JR ;

WALKER, GC ;

DEVORET, R .

JOURNAL OF BACTERIOLOGY, 1989, 171 (05) :2415-2423

[7] THE GROES AND GROEL HEAT-SHOCK GENE-PRODUCTS OF ESCHERICHIA-COLI ARE ESSENTIAL FOR BACTERIAL-GROWTH AT ALL TEMPERATURES [J].

FAYET, O ;

ZIEGELHOFFER, T ;

GEORGOPOULOS, C .

JOURNAL OF BACTERIOLOGY, 1989, 171 (03) :1379-1385

[8] CONTRIBUTION OF 3'-]5' EXONUCLEASE ACTIVITY OF DNA POLYMERASE-III HOLOENZYME FROM ESCHERICHIA-COLI TO SPECIFICITY [J].

FERSHT, AR ;

KNILLJONES, JW .

JOURNAL OF MOLECULAR BIOLOGY, 1983, 165 (04) :669-682

[9] IDENTIFICATION OF ALTERED BASES IN MUTATED SINGLE-STRANDED DNA .3. MUTAGENESIS BY ULTRAVIOLET LIGHT [J].

HOWARD, BD ;

TESSMAN, I .

JOURNAL OF MOLECULAR BIOLOGY, 1964, 9 (02) :372-&

[10] GROEL AND DNAK GENES OF ESCHERICHIA-COLI ARE INDUCED BY UV IRRADIATION AND NALIDIXIC-ACID IN AN HTPR+-DEPENDENT FASHION [J].

KRUEGER, JH ;

WALKER, GC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (05) :1499-1503