CYTOCHEMICAL DEMONSTRATION OF ASPARTATE-AMINOTRANSFERASE ACTIVITY IN THE RAT RETINA

被引：19

作者：

GEBHARD, R ^{[1
]}

机构：

[1] UNIV WURZBURG, DEPT ANAT, W-8700 WURZBURG, GERMANY

来源：

BRAIN RESEARCH | 1991年 / 539卷 / 02期

关键词：

ASPARTATE AMINOTRANSFERASE; CYTOCHEMISTRY; GLUTAMATE; RAT RETINA;

D O I：

10.1016/0006-8993(91)91641-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The mitochondrial (m-AAT) and the cytoplasmic (c-AAT) isoenzyme activities of the glutamate synthesizing enzyme aspartate aminotransferase have been localized in the rat retina on the ultrastructural level using enzyme histochemistry. Reaction product of c-AAT was found selectively in clone pedicles, in presynaptic terminals of a subpopulation of amacrine cells and of horizontal cell processes, which are connected to rods. Rod spherules, terminals of cone-related horizontal cells and of bipolar cells reacted negatively, as well as ganglion cells, nerve fibre layer and optic nerve. m-AAT reaction product was found in all neuronal structures, most densely in the photoreceptor inner segments. The localization of c-AAT activity is in accordance with its presumed meaning in the production of releasable glutamate.

引用

页码：337 / 341

页数：5

共 30 条

[1] RESPONSES MEDIATED BY EXCITATORY AMINO-ACID RECEPTORS IN SOLITARY RETINAL GANGLION-CELLS FROM RAT [J].