HUMAN CHOLINE-ACETYLTRANSFERASE (CHAT) - PARTIAL GENE SEQUENCE AND POTENTIAL CONTROL REGIONS

被引：26

作者：

TOUSSAINT, JL

GEOFFROY, V

SCHMITT, M

WERNER, A

GARNIER, JM

SIMONI, P

KEMPF, J

机构：

[1] FAC MED STRASBOURG,INST CHIM BIOL,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE

[2] KANTONSSPITAL ZLF,GEFASSPHYSIOL LAB 319,CH-4031 BASEL,SWITZERLAND

[3] LAB GENET MOLEC EUCARYOTES,F-67085 STRASBOURG,FRANCE

来源：

GENOMICS | 1992年 / 12卷 / 02期

关键词：

D O I：

10.1016/0888-7543(92)90395-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Choline acetyltransferase (CHAT) (EC2.3.1.6) is the biosynthetic enzyme for the neurotransmitter acetylcholine in the central and peripheral nervous systems. In this study, a human CHAT genomic clone has been isolated and partially sequenced at its 5′ end. This fragment contains the first four exons with an ACG initiator codon and potential control regions including TATA, CAAT, GC boxes, and several transcription control sequences. A comparison of the primary structure of CHAT among pig, rat, mouse, and Drosophila is presented. © 1992.

引用

页码：412 / 416

页数：5

共 21 条

[1] DIRECT MAPPING OF ADENO-ASSOCIATED VIRUS CAPSID PROTEIN-B AND PROTEIN-C - A POSSIBLE ACG INITIATION CODON
BECERRA, SP
ROSE, JA
HARDY, M
BAROUDY, BM
ANDERSON, CW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (23) : 7919 - 7923
[2] CDNA CLONING AND COMPLETE SEQUENCE OF PORCINE CHOLINE-ACETYLTRANSFERASE - INVITRO TRANSLATION OF THE CORRESPONDING RNA YIELDS AN ACTIVE PROTEIN
BERRARD, S
BRICE, A
LOTTSPEICH, F
BRAUN, A
BARDE, YA
MALLET, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) : 9280 - 9284
[3] MOLECULAR GENETIC APPROACH TO THE STUDY OF MAMMALIAN CHOLINE-ACETYLTRANSFERASE
BERRARD, S
BRICE, A
MALLET, J
[J]. BRAIN RESEARCH BULLETIN, 1989, 22 (01) : 147 - 153
[4] HUNTINGTONS-CHOREA - POSTMORTEM MEASUREMENT OF GLUTAMIC-ACID DECARBOXYLASE, CHOLINE-ACETYLTRANSFERASE AND DOPAMINE IN BASAL GANGLIA
BIRD, ED
IVERSEN, LL
[J]. BRAIN, 1974, 97 (SEP) : 457 - 472
[5] COMPLETE SEQUENCE OF A CDNA-ENCODING AN ACTIVE-RAT CHOLINE-ACETYLTRANSFERASE - A TOOL TO INVESTIGATE THE PLASTICITY OF CHOLINERGIC PHENOTYPE EXPRESSION
BRICE, A
BERRARD, S
RAYNAUD, B
ANSIEAU, S
COPPOLA, T
WEBER, MJ
MALLET, J
[J]. JOURNAL OF NEUROSCIENCE RESEARCH, 1989, 23 (03) : 266 - 273
[6] PROMOTER SEQUENCES OF EUKARYOTIC PROTEIN-CODING GENES
CORDEN, J
WASYLYK, B
BUCHWALDER, A
CORSI, PS
KEDINGER, C
CHAMBON, P
[J]. SCIENCE, 1980, 209 (4463) : 1406 - 1414
[7] RIBOSOMAL INITIATION FROM AN ACG CODON IN THE SENDAI VIRUS P/C MESSENGER-RNA
CURRAN, J
KOLAKOFSKY, D
[J]. EMBO JOURNAL, 1988, 7 (01) : 245 - 251
[8] Dayhoff MO, 1978, ATL PROTEIN SEQ STRU, V5, P345
[9] GUPTA KC, 1988, J BIOL CHEM, V263, P8553
[10] CONSERVATION OF AMINO-ACID SEQUENCES BETWEEN HUMAN AND PORCINE CHOLINE-ACETYLTRANSFERASE
HERSH, LB
TAKANE, K
GYLYS, K
MOOMAW, C
SLAUGHTER, C
[J]. JOURNAL OF NEUROCHEMISTRY, 1988, 51 (06) : 1843 - 1845

← 1 2 3 →