NEW METHOD OF QUATERNIZING AMINES AND ITS USE IN AMINO-ACID AND PEPTIDE CHEMISTRY

被引：105

作者：

CHEN, FCM ^{[1
]}

BENOITON, NL ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT BIOCHEM,OTTAWA K1N 9A9,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1976年 / 54卷 / 20期

关键词：

Peptides - Potassium compounds;

D O I：

10.1139/v76-475

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methyl iodide and potassium bicarbonate in methanol is presented as a mild, efficient, and selective reagent for the quaternization of amino groups. It does not attack hydroxyl groups. Its use with amino acids, derivatives of lysine, and small peptides is described.

引用

页码：3310 / 3311

页数：2

共 8 条

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BENOITON, NL
[J]. CANADIAN JOURNAL OF BIOCHEMISTRY, 1970, 48 (10): : 1122 - &
[7] ALKYLATION OF AMINES - GENERAL EXHAUSTIVE ALKYLATION METHOD FOR SYNTHESIS OF QUATERNARY AMMONIUM COMPOUNDS
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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (06) : 824 - &
[8] TAKEMOTO T, 1964, Yakugaku Zasshi, V84, P1180

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