LOCALIZATION OF THE GENE FOR PLASMA RETINOL BINDING-PROTEIN TO THE DISTAL HALF OF MOUSE CHROMOSOME-19

被引：12

作者：

CHAINANI, M ^{[1
]}

SAMPSELL, B ^{[1
]}

ELLIOTT, RW ^{[1
]}

机构：

[1] SUNY COLL BUFFALO,DEPT BIOL,BUFFALO,NY 14222

来源：

GENOMICS | 1991年 / 9卷 / 02期

关键词：

D O I：

10.1016/0888-7543(91)90269-K

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A DNA polymorphism for the mouse retinol binding protein has been identified using the enzyme BamIII and a rat partial cDNA probe. Analysis of the polymorphism in DNA from 64 inbred mouse strains demonstrated the presence of a single gene with two alleles, Rbp-4b and Rbp-4d. Comparison of the segregation patterns of these alleles in three sets of recombinant inbred strains with allele segregation patterns of previously characterized loci shows that the Rbp-4 locus is closely linked to the locus for phenobarbital-inducible cytochrome P450-2c (Cyp-2c) that has been shown by in situ hybridization to lie on chromosome 19, bands D1-D2. The Rbp-4 locus is just proximal to Cyp-2c at the distal end of chromosome 19. © 1991.

引用

页码：376 / 379

页数：4

共 30 条

[1]

BAUMANN H, 1985, MOL GEN GENET, V210, P505

[2] MAPPING THE STRUCTURAL GENES-CODING FOR THE MAJOR URINARY PROTEINS IN THE MOUSE - COMBINED USE OF RECOMBINANT INBRED STRAINS AND SOMATIC-CELL HYBRIDS [J].