INSIGHT INTO TOPOLOGICAL AND FUNCTIONAL-RELATIONSHIPS OF CYTOCHROME-C-OXIDASE SUBUNIT-I OF SACCHAROMYCES-CEREVISIAE BY MEANS OF INTRAGENIC COMPLEMENTATION

被引：15

作者：

MEUNIER, B

COSTER, F

LEMARRE, P

COLSON, AM

机构：

[1] Université Catholique de Louvain, Laboratoire de Génétique Microbienne, 1348 Louvain-la-Neuve

来源：

FEBS LETTERS | 1993年 / 321卷 / 2-3期

关键词：

CYTOCHROME-C OXIDASE; YEAST; INTRAGENIC COMPLEMENTATION; MODELS;

D O I：

10.1016/0014-5793(93)80099-G

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In yeast, revertants were selected from four respiratory deficient mutants carrying mutations in the cytochrome c oxidase subunit I gene. Intragenic second site mutations revealed amino acids which are functionally complementary to the original mutated position and may be in topological interaction with it. The results provide additional data in favour of the model proposed for the structure of the binuclear centre in proton-motive oxidase.

引用

页码：159 / 162

页数：4

共 13 条

[1] BINUCLEAR CENTER STRUCTURE OF TERMINAL PROTONMOTIVE OXIDASES [J].