PERINATAL UNDERNUTRITION REDUCED ETHANOL INTAKE PREFERENCE IN ADULT RECOVERED RATS

被引：18

作者：

CORDOBA, NE ^{[1
]}

MOLINA, JC ^{[1
]}

BASSO, AM ^{[1
]}

ORSINGHER, OA ^{[1
]}

机构：

[1] INST INVEST MED M&M FERREYRA,CORDOBA,SPAIN

来源：

PHYSIOLOGY & BEHAVIOR | 1990年 / 47卷 / 06期

关键词：

Ethanol intake; Ethanol odor; Perinatal undernutrition; Taste aversion;

D O I：

10.1016/0031-9384(90)90360-G

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Adult female rats submitted to a protein deprivation schedule at perinatal age (from 14th day of fetal life until 50 days of age) were tested for alcohol intake in a preference test. When compared with control animals, experimental rats exhibited higher overall fluid intake. Nevertheless, in terms of ethanol preference these subjects evidenced lower preference to this drug. A test for assessing ethanol olfactory preference did not show any differences between control and experimental rats in basal conditions. However, after repeated exposure to alcohol, deprived rats showed an aversion to ethanol odor, while controls evidenced the opposite effect, i.e., heightened preference. Possible differences to the aversive effects of ethanol between control and experimental animals were assayed by means of two taste aversion tests, by associating alcohol to sucrose or NaCl. No differences were detected between both groups of rats. These results demonstrate that early undernutrition reduces ethanol preference in a free choice situation. Such an effect could be due, at least partially, to odor aversion developed by repeated exposure. © 1990.

引用

页码：1111 / 1116

页数：6

共 21 条

[1] ZIMELDINE - A REVIEW OF ITS EFFECTS ON ETHANOL-CONSUMPTION [J].