DIRECT SEPARATION OF AMINO-ACID ENANTIOMERS USING A CHIRAL CROWN-ETHER STATIONARY PHASE - APPLICATION TO 2-AMINO-OMEGA-PHOSPHONOALKANOIC ACIDS

被引:26
作者
UDVARHELYI, PM
SUNTER, DC
WATKINS, JC
机构
[1] Department of Pharmacology, School of Medical Sciences, University of Bristol, Bristol, Avon
来源
JOURNAL OF CHROMATOGRAPHY | 1990年 / 519卷 / 01期
关键词
D O I
10.1016/0021-9673(90)85135-I
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The resolution of a series of 2-amino-ω-phosphonoalkanoic acid enantiomers using a crown ether chiral stationary phase is described. The method is applicable to other primary amino acid and shows some advantages over chiral derivatization with fluorometric detection. Optical isomers of under 0.5% may be quantified. © 1990.
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页码:69 / 74
页数:6
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