EVALUATION OF THE ELBS PERSULFATE OXIDATION REACTION FOR THE PREPARATION OF ARYLOXYPHENOXYPROPIONATE HERBICIDES

被引：6

作者：

WATSON, KG ^{[1
]}

SERBAN, A ^{[1
]}

机构：

[1] ICI AUSTRALIA RES GRP,ASCOT,VIC 3032,AUSTRALIA

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1995年 / 48卷 / 08期

关键词：

D O I：

10.1071/CH9951503

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new, simple method for the preparation of several 4-(aryloxy)phenols (2a-d) and alkyl 2-(4-hydroxyphenoxy)propionates (3a,b) is described. These compounds are key precursors for the synthesis of important aryloxyphenoxypropionate herbicides (1a-d). The method uses the Elbs persulfate oxidation to convert phenol into 4-hydroxyphenyl sulfate (5). The free hydroxy group is then reacted with various aryl halides and alkyl 2-halopropionates. Mild hydrolysis of the sulfate group with boiling acetic acid then gives the products (2a-d) and (3a,b), generally in modest to good yield.

引用

页码：1503 / 1509

页数：7

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