SYNTHESIS AND EVALUATION OF N,N-DI-N-PROPYLTETRAHYDROBENZ[F]INDOL-7-AMINE AND RELATED CONGENERS AS DOPAMINERGIC AGONISTS

被引：22

作者：

NICHOLS, DE ^{[1
]}

CASSADY, JM ^{[1
]}

PERSONS, PE ^{[1
]}

YEUNG, MC ^{[1
]}

CLEMENS, JA ^{[1
]}

SMALSTIG, EB ^{[1
]}

机构：

[1] ELI LILLY INT CORP,LILLY RES LABS,INDIANAPOLIS,IN 46206

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 09期

关键词：

D O I：

10.1021/jm00129a017

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2128 / 2134

页数：7

共 25 条

[1]

ASAHINA Y, 1944, J PHARM SOC JPN, V64, P153

[2] DRUG DESIGN VIA PHARMACOPHORE IDENTIFICATION - DOPAMINERGIC ACTIVITY OF 3H-BENZ[E]INDOL-8-AMINES AND THEIR MODE OF INTERACTION WITH THE DOPAMINE RECEPTOR [J].

ASSELIN, AA ;

HUMBER, LG ;

VOITH, K ;

METCALF, G .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (05) :648-654

[3] EMETIC ACTIVITY OF N-SUBSTITUTED NORAPOMORPHINES [J].

ATKINSON, ER ;

BULLOCK, FJ ;

GRANCHELLI, FE ;

ARCHER, S ;

ROSENBERG, FJ ;

TEIGER, DG ;

NACHOD, FC .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (10) :1000-1003

[4] BICYCLIC AND TRICYCLIC ERGOLINE PARTIAL STRUCTURES - RIGID 3-(2-AMINOETHYL)PYRROLES AND 3-(2-AMINOETHYL)PYRAZOLE AND 4-(2-AMINOETHYL)PYRAZOLE AS DOPAMINE AGONISTS [J].

BACH, NJ ;

KORNFELD, EC ;

JONES, ND ;

CHANEY, MO ;

DORMAN, DE ;

PASCHAL, JW ;

CLEMENS, JA ;

SMALSTIG, EB .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (05) :481-491

[5] CONVERSION OF ERGOLINES TO HEXAHYDROBENZO[F]QUINOLINES AND OCTAHYDROBENZO[F]QUINOLINES (DEPYRROLOERGOLINES) [J].

BACH, NJ ;

KORNFELD, EC ;

CLEMENS, JA ;

SMALSTIG, EB .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (07) :812-814

[6] MONOQUATERNARY NEUROMUSCULAR BLOCKING-AGENTS BASED ON 1-TETRALONE AND 1-INDANONE [J].

BIGGS, DF ;

CASY, AF ;

CHU, I ;

COUTTS, RT .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (04) :472-475

[7] S(+)APOMORPHINES - SELECTIVE-INHIBITION OF EXCITATORY EFFECTS OF DOPAMINE INJECTED INTO THE LIMBIC SYSTEM OF THE RAT [J].

CAMPBELL, A ;

BALDESSARINI, RJ ;

TEICHER, MH ;

NEUMEYER, JL .

NEUROPHARMACOLOGY, 1985, 24 (05) :391-399

[8] PROPOSED DOPAMINERGIC PHARMACOPHORE OF LERGOTRILE, PERGOLIDE, AND RELATED ERGOT ALKALOID DERIVATIVES [J].

CANNON, JG ;

DEMOPOULOS, BJ ;

LONG, JP ;

FLYNN, JR ;

SHARABI, FM .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (03) :238-240

[9] 6-HYDROXY-4-[2-(DI-NORMAL-PROPYLAMINO)ETHYL]INDOLE - SYNTHESIS AND DOPAMINERGIC ACTIONS [J].

CANNON, JG ;

LEE, T ;

ILHAN, M ;

KOONS, J ;

LONG, JP .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (03) :386-389

[10] SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF N,N-DI-N-PROPYLDOPAMINE CONGENERS CONTAINING PHENOLIC BIOISOSTERES [J].

CLARK, RD ;

CAROON, JM ;

ISAAC, NE ;

MCCLELLAND, DL ;

MICHEL, AD ;

PETTY, TA ;

ROSENKRANZ, RP ;

WATERBURY, LD .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1987, 76 (05) :411-415

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