PLANTS OF NEW-CALEDONIA .138. APOTIRUCALLANE TRITERPENES FROM DYSOXYLUM-ROSEUM

被引：18

作者：

ADESANYA, SA ^{[1
]}

PAIS, M ^{[1
]}

SEVENET, T ^{[1
]}

COSSON, JP ^{[1
]}

机构：

[1] CNRS,PLANTES MED LAB,NOUMEA,NEW CALEDONIA

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 06期

关键词：

D O I：

10.1021/np50078a015

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Chemical investigation of the biologically active compounds in Dysoxylum roseum leaves has led to the isolation and characterization of five new apotirucallane-derived triterpenes, dysorones A [1], B [2], C [3], D [4], and E [5], and beta-sitosterol. The major compound, dysorone E [5], exhibits moderate cytotoxic activity in vitro against the growth of KB human buccal carcinoma cells (ED50 3.5-mu-g/ml).

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页码：1588 / 1594

页数：7

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