DIRECT DETERMINATION OF THE SEQUENCE OF DESTRUXINS (CYCLODEPSIPEPTIDES) USING NEGATIVE-ION FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY

被引：11

作者：

LANGE, C

MULHEIM, C

VEY, A

PAIS, M

机构：

[1] UNIV PARIS 06,CHIM ORGAN STRUCT LAB,CNRS,UA 455,F-75230 PARIS 05,FRANCE

[2] INRA,PATHOL COMPAREE STN,CNRS,URA 11840,F-30380 ST CHRISTOL ALES,FRANCE

[3] CNRS,INST CHIM SUBST NAT 92,F-91190 GIF SUR YVETTE,FRANCE

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 02期

关键词：

D O I：

10.1002/rcm.1290050209

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Fast-atom bombardment negative-ion mass spectra of various natural destruxins (cyclodepsipeptides) using a glycerol matrix are investigated to clarify their regular pattern of fragmentation. Deprotonated molecules allow characterization of the molecular weight. Also, at lower masses, anions Y(i)'- of significant intensities permit the determination of their amino acid sequences.

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页码：86 / 91

页数：6

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