THE PERSISTENCE OF SPIROCHETAL NUCLEIC-ACIDS IN ACTIVE LYME ARTHRITIS

被引：77

作者：

BRADLEY, JF

JOHNSON, RC

GOODMAN, JL

机构：

[1] UNIV MINNESOTA, SCH MED, DEPT MED, INFECT DIS SECT, MINNEAPOLIS, MN 55455 USA

[2] UNIV MINNESOTA, SCH MED, DEPT MICROBIOL, MINNEAPOLIS, MN 55455 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1994年 / 120卷 / 06期

关键词：

D O I：

10.7326/0003-4819-120-6-199403150-00007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Intra-articular persistence of Borrelia burgdorferi nucleic acids in Lyme arthritis, as shown by prospective culture and polymerase chain reaction studies, suggests that persistent organisms and their components are important in maintaining ongoing immune and inflammatory processes.

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收藏

页码：487 / 489

页数：3

相关论文

共 13 条

[1]

BARBOUR AG, 1984, YALE J BIOL MED, V57, P521

[2]

BECK G, 1989, J RHEUMATOL, V16, P800

[3] FAILURE OF TETRACYCLINE THERAPY IN EARLY LYME-DISEASE [J].

DATTWYLER, RJ ;

HALPERIN, JJ .

ARTHRITIS AND RHEUMATISM, 1987, 30 (04) :448-450

[4] MOLECULAR-DETECTION OF PERSISTENT BORRELIA-BURGDORFERI IN THE URINE OF PATIENTS WITH ACTIVE LYME-DISEASE [J].

GOODMAN, JL ;

JURKOVICH, P ;

KRAMBER, JM ;

JOHNSON, RC .

INFECTION AND IMMUNITY, 1991, 59 (01) :269-278

[5] IMMUNE-COMPLEXES AND THE EVOLUTION OF LYME ARTHRITIS - DISSEMINATION AND LOCALIZATION OF ABNORMAL C1Q BINDING-ACTIVITY [J].

HARDIN, JA ;

STEERE, AC ;

MALAWISTA, SE .

NEW ENGLAND JOURNAL OF MEDICINE, 1979, 301 (25) :1358-1363

[6]

JOHNSTON YE, 1985, AM J PATHOL, V118, P26

[7] THE POLYMERASE CHAIN-REACTION FOR THE DETECTION OF BORRELIA-BURGDORFERI IN HUMAN-BODY FLUIDS [J].

LIEBLING, MR ;

NISHIO, MJ ;

RODRIGUEZ, A ;

SIGAL, LH ;

JIN, T ;

LOUIE, JS .

ARTHRITIS AND RHEUMATISM, 1993, 36 (05) :665-675

[8]

Rys Paul N., 1993, P203

[9] CULTIVATION OF BORRELIA-BURGDORFERI FROM JOINT FLUID 3 MONTHS AFTER TREATMENT OF FACIAL PALSY DUE TO LYME BORRELIOSIS [J].

SCHMIDLI, J ;

HUNZIKER, T ;

MOESLI, P ;

SCHAAD, UB .

JOURNAL OF INFECTIOUS DISEASES, 1988, 158 (04) :905-906

[10] BORRELIA-BURGDORFERI IN JOINT FLUID IN CHRONIC LYME ARTHRITIS [J].

SNYDMAN, DR ;

SCHENKEIN, DP ;

BERARDI, VP ;

LASTAVICA, CC ;

PARISER, KM .

ANNALS OF INTERNAL MEDICINE, 1986, 104 (06) :798-800