RELAPSE OF TUBERCULOSIS IN A PATIENT WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME DESPITE 12 MONTHS OF ANTITUBERCULOUS THERAPY AND CONTINUATION OF ISONIAZID

被引:12
作者
SHAFER, RW [1 ]
JONES, WD [1 ]
机构
[1] CTR DIS CONTROL,DIV BACTERIAL DIS,ATLANTA,GA 30333
来源
TUBERCLE | 1991年 / 72卷 / 02期
关键词
D O I
10.1016/0041-3879(91)90043-R
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
A 33-year-old man with AIDS and pleuro-pulmonary tuberculosis was treated with a combination of antituberculous medications for 12 months and with continuation of isoniazid. A total of 2 months after completing combination therapy the patient developed fever, malaise, and anorexia. Mycobacterial blood cultures grew M. tuberculosis and the patient improved with the readministration of rifampicin and pyrazinamide. Phage typing of the patient's isolates of M. tuberculosis confirmed that he had experienced a relapse and not a reinfection. The patient had received 5 months of his treatment while hospitalised. We believe he was compliant with therapy outside the hospital because he attended all of his clinic appointments. Follow-up studies of HIV-infected patients with tuberculosis are therefore needed.
引用
收藏
页码:149 / 151
页数:3
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