INVITRO ACTIVITY OF CHLORHEXIDINE AGAINST ENTERIC RODS, PSEUDOMONADS AND ACINETOBACTER FROM HUMAN PERIODONTITIS

被引:44
作者
SLOTS, J
RAMS, TE
SCHONFELD, SE
机构
[1] University of Southern California School of Dentistry, Los Angeles, California
来源
ORAL MICROBIOLOGY AND IMMUNOLOGY | 1991年 / 6卷 / 01期
关键词
ENTERIC RODS; PSEUDOMONADS; ACINETOBACTER; PERIODONTAL MICROBIOLOGY; CHLORHEXIDINE; INVITRO SUSCEPTIBILITY;
D O I
10.1111/j.1399-302X.1991.tb00452.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Fifty-eight periodontal isolates of the families Enterobacteriaceae and Pseudomonadaceae, and the genera Acinetobacter and Achromobacter were studied to determine their susceptibility to Peridex(R) (0.12% chlorhexidine digluconate solution; Procter & Gamble). In an agar dilution assay, about 50% of the study strains grew in the presence of 70 mu-g/ml of chlorhexidine. Enterobacter cloacae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Pseudomonas cepacia, and Serratia marcescens comprised the most resistant species. Studies are needed to determine the microbiological and clinical effects of chlorhexidine usage in patients infected with enteric rods and pseudomonads.
引用
收藏
页码:62 / 64
页数:3
相关论文
共 26 条
[1]  
Alcoforado GAP, Rams TE, Feik D, Slots J
[2]  
Bergmann OJ, Oral infections and septicemias in immunocompromised patients with hematologic malignancies, J Clin Microbiol, 26, pp. 2105-2109, (1988)
[3]  
Bergmann OJ, Kilian M, Ellegaard J, Potentially pathogenic microorganisms in the oral cavity during febrile episodes in immunocompromised patients with haematologic malignancies, Scand J Infect Dis, 21, pp. 43-51, (1989)
[4]  
Brown AT, Sims RE, Raybould TP, Lillich TT, Henslee PJ, Ferretti GA, Oral gram‐negative bacilli in bone marrow transplant patients given chlorhexidine rinses, J Dent Res, 68, pp. 1199-1204, (1989)
[5]  
Emilson CG, Susceptibility of various microorganisms to chlorhexidine, Scand J Dent Res, 85, pp. 255-265, (1977)
[6]  
Emilson CG, Fornell J, Effect of tooth‐brushing with chlorhexidine gel on salivary microflora, oral hygiene and caries, Scand J Dent Res, 84, pp. 308-319, (1976)
[7]  
Ferretti GA, Ash RC, Brown AT, Parr MD, Romond EH, Lillich TT, Control of oral mucositis and candidiasis in marrow transplantation: a prospective, double blind trial of chlorhexidine digluconate oral rinse, Bone Marrow Trans, 3, pp. 483-494, (1988)
[8]  
Ferretti GA, Raybould TP, Brown AT, Et al., Chlorhexidine prophylaxis for chemotherapy and radiotherapy‐induced stomatitis: a randomized double‐blind trial, Oral Surg Oral Med Oral Pathol, 69, pp. 331-338, (1990)
[9]  
Flotra L, Gjermo P, Rolla G, Waerhaug J, Side effects of chlorhexidine mouthwashes, Scand J Dent Res, 79, pp. 119-125, (1971)
[10]  
Gjermo P, Chlorhexidine and related compounds, J Dent Res, 68, pp. 1602-1608, (1989)