A CONFORMATIONAL STUDY ON CYCLO[(S)-PHENYLALANYL-(S)-HISTIDYL] BY MOLECULAR MODELING AND NMR TECHNIQUES

被引：22

作者：

NORTH, M

机构：

[1] Department of Chemistry, University of Wales, Bangor

来源：

TETRAHEDRON | 1992年 / 48卷 / 26期

关键词：

CYCLO[(S)-PHENYLALANYL-(S)-HISTIDYL; CONFORMATION; HYDROCYANATION; MOLECULAR MODELING; NMR;

D O I：

10.1016/S0040-4020(01)88304-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The conformation of the cyclic dipeptide cyclo[(S)-Phenylalanyl-(S)-Histidyl] is investigated by molecular modelling and NMR techniques. The results are of interest when considering the mechanism by which this compound acts as a catalyst for the asymmetric addition of HCN to aldehydes.

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页码：5509 / 5522

页数：14

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