PYRIDOXAL 5'-PHOSPHATE MEDIATED INACTIVATION OF ESCHERICHIA-COLI DNA-POLYMERASE-I - IDENTIFICATION OF LYSINE-635 AS AN ESSENTIAL RESIDUE FOR THE PROCESSIVE MODE OF DNA-SYNTHESIS

被引：35

作者：

BASU, S ^{[1
]}

BASU, A ^{[1
]}

MODAK, MJ ^{[1
]}

机构：

[1] UNIV MED & DENT NEW JERSEY,NEW JERSEY MED SCH,DEPT BIOCHEM,NEWARK,NJ 07103

来源：

BIOCHEMISTRY | 1988年 / 27卷 / 18期

关键词：

D O I：

10.1021/bi00418a011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：6710 / 6716

页数：7

相关论文

共 19 条

[1] AFFINITY LABELING OF ESCHERICHIA-COLI DNA-POLYMERASE-I WITH THYMIDINE 5'-TRIPHOSPHATE AND 8-AZIDOADENOSINE 5'-TRIPHOSPHATE - CONDITIONS FOR OPTIMUM LABELING, SPECIFICITY, AND IDENTIFICATION OF THE LABELING SITE
ABRAHAM, KI
MODAK, MJ
[J]. BIOCHEMISTRY, 1984, 23 (06) : 1176 - 1182
[2] BASU A, 1987, J BIOL CHEM, V262, P9601
[3] IDENTIFICATION AND AMINO-ACID-SEQUENCE OF THE DEOXYNUCLEOSIDE TRIPHOSPHATE BINDING-SITE IN ESCHERICHIA-COLI DNA-POLYMERASE-I
BASU, A
MODAK, MJ
[J]. BIOCHEMISTRY, 1987, 26 (06) : 1704 - 1709
[4] BENESCH R, 1982, J BIOL CHEM, V257, P1320
[5] DETERA SD, 1982, J BIOL CHEM, V257, P9770
[6] NUCLEAR OVERHAUSER EFFECT STUDIES OF THE CONFORMATIONS AND BINDING-SITE ENVIRONMENTS OF DEOXYNUCLEOSIDE TRIPHOSPHATE SUBSTRATES BOUND TO DNA-POLYMERASE-I AND ITS LARGE FRAGMENT
FERRIN, LJ
MILDVAN, AS
[J]. BIOCHEMISTRY, 1985, 24 (24) : 6904 - 6913
[7] SITE-SPECIFIC MODIFICATION OF ESCHERICHIA-COLI DNA-POLYMERASE-I LARGE FRAGMENT WITH PYRIDOXAL 5'-PHOSPHATE
HAZRA, AK
DETERAWADLEIGH, S
WILSON, SH
[J]. BIOCHEMISTRY, 1984, 23 (09) : 2073 - 2078
[8] CONSTRUCTION OF A PLASMID THAT OVERPRODUCES THE LARGE PROTEOLYTIC FRAGMENT (KLENOW FRAGMENT) OF DNA-POLYMERASE-I OF ESCHERICHIA-COLI
JOYCE, CM
GRINDLEY, NDF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (07): : 1830 - 1834
[9] JOYCE CM, 1982, J BIOL CHEM, V257, P1958
[10] MERRIL BM, 1984, J BIOL CHEM, V257, P1320