1,3-AMINOALCOHOLS BY REDUCTIVE CLEAVAGE OF ISOXAZOLIDINES WITH MOLYBDENUM HEXACARBONYL

被引：222

作者：

CICCHI, S

GOTI, A

BRANDI, A

GUARNA, A

DESARLO, F

机构：

[1] DIPARTIMENTO CHIM ORGAN,VIA G CAPPONI 9,I-50121 FLORENCE,ITALY

[2] UNIV BASILICATA,DIPARTIMENTO CHIM,I-85100 POTENZA,ITALY

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)89062-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isoxazolidines are reductively cleaved to 1,3-aminoalcohols by reacting with Mo(CO)6 and water. Reaction conditions are simple, mild and selective giving good yields of highly functionalized products with complete retention of configuration of the stereocenters. The reduction fails when steric hindrance is experienced by the nitrogen atom. © 1990.

引用

页码：3351 / 3354

页数：4

共 28 条

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