COEXPRESSION OF VIMENTIN AND CYTOKERATINS IN M-CELLS OF RABBIT INTESTINAL LYMPHOID FOLLICLE-ASSOCIATED EPITHELIUM

被引:79
作者
JEPSON, MA
MASON, CM
BENNETT, MK
SIMMONS, NL
HIRST, BH
机构
[1] UNIV NEWCASTLE UPON TYNE,SCH MED,DEPT PHYSIOL SCI,NEWCASTLE TYNE NE2 4HH,ENGLAND
[2] UNIV NEWCASTLE UPON TYNE,SCH MED,GASTROINTESTINAL DRUG DELIVERY RES CTR,NEWCASTLE TYNE NE2 4HH,ENGLAND
[3] UNIV NEWCASTLE UPON TYNE,SCH MED,DIV PATHOL,NEWCASTLE TYNE NE2 4HH,ENGLAND
来源
HISTOCHEMICAL JOURNAL | 1992年 / 24卷 / 01期
关键词
D O I
10.1007/BF01043285
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Membranous epithelial (M) cells within the follicle-associated epithelium which overlies gut-associated lymphoid tissue in Peyer's patches and of appendix have been shown by immunocytochemical staining, in rabbit, to contain both vimentin- and cytokeratin-type intermediate filaments. The specificity of vimentin immunostaining has been confirmed by blocking with purified vimentin and by immunoblotting. No evidence was obtained for the expression of vimentin in rat, mouse or human M cells. The possible significance of vimentin-expression in these specialized epithelial cells and the potential use of vimentin as a positive marker for M cells are discussed.
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页码:33 / 39
页数:7
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