INVESTIGATION ON PHOSPHATE DEPENDENT GLUTAMINASE (EC 3.5.1.2) ACTIVITY IN HOST TISSUES OF EAC-BEARING MICE AND RESPONSE OF LIVER EC 3.5.1.2 ON CU-ATP THERAPY

被引：9

作者：

PAL, S

NAYAK, KK

MAITY, P

机构：

[1] CHITTARANJAN NATL CANC INST,DEPT CELL BIOL,37 SP MUKHERJEE RD,CALCUTTA 700026,INDIA

[2] PD COLL,DEPT CHEM,NADIA 741152,W BENGAL,INDIA

来源：

CANCER LETTERS | 1991年 / 58卷 / 1-2期

关键词：

GLUTAMINASE; EHRLICH ASCITES TUMOR; COPPER-ATP COMPLEX; CU-ATP THERAPY; MOUSE LIVER;

D O I：

10.1016/0304-3835(91)90038-J

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Phosphate-dependent glutaminase activity in spleen, kidney, brain and liver is increased after tumor cell inoculation and this activity gradually increases with the progression of the tumor. The increase in enzyme activity in the liver is significant. Studies of the response of liver glutaminase after Cu-ATP treatment reveals that Cu-ATP is capable of reducing the high glutaminase level in subjects with malignant tumors to the normal level.

引用

页码：151 / 153

页数：3

共 14 条

[1] INTERACTION OF ADENOSINE 5' TRIPHOSPHATE WITH SOME DIPOSITIVE METAL-IONS AND ISOLATION AND CHARACTERIZATION OF SOME NOVEL SOLID COMPOUNDS [J].