MILD DEPROTECTION OF STEROID ESTERS BY BIS(TRIBUTYLTIN)OXIDE

被引：15

作者：

PEREZ, MG ^{[1
]}

MAIER, MS ^{[1
]}

机构：

[1] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,DEPT QUIM ORGAN,RA-1428 BUENOS AIRES,DF,ARGENTINA

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 19期

关键词：

D O I：

10.1016/0040-4039(95)00616-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bis(tributyltin)oxide (BBTO) has been utilized Tor the first time for the deprotection of steroid esters. The best results were obtained for 3 beta-esters, in particular the selective hydrolysis of the 3 beta-acetyl group in 3 beta,6 alpha-diacetoxy-5 alpha-pregnan-20-one to give 6 alpha-acetoxy-3 beta-hydroxy-5 alpha-pregnan-20-one.

引用

页码：3311 / 3314

页数：4

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